EASD 2024 in Madrid
At the 60th annual EASD 2024 conference in Madrid, we presented our AID solution myLoop powered by CamAPS FX, designed and licensed for use in pregnancy. Prof. Helen Murphy and Dr. Pilar Beato-Víbora demonstrated how pregnant women managing their type 1 diabetes can be counselled and cared for with myLoop at every stage of their pregnancy, with the aim of shortening the planning phase, achieving safe pregnancies and deliveries, and caring for healthy mothers.
Pregnant women with Type 1 Diabetes (T1D) tend to have large babies, approximately 50% of them will have babies with Large for Gestational Age (LGA). LGA is associated with preterm birth and the need for neonatal intensive care support. In utero exposure to hyperglycaemia predisposes babies to obesity, cardiovascular disease, Type 2 Diabetes, and neurocognitive issues, such as Autism Spectrum Disorder, later in life.
Achieving the therapy goals with myLoop
In our Hot Topic session, Prof. Helen Murphy and Dr. Pilar Beato-Víbora explained how AID systems help women with type 1 diabetes achieve their glucose targets during pregnancy.
Prof. Murphy emphasised that strict glycaemic targets are essential both in planning and during pregnancy to avoid complications. myLoop makes it easier for women to achieve these goals because the CamAPS FX algorithm continuously adjusts insulin delivery.
Dr. Pilar Beato-Víbora used case studies and real data to demonstrate how myLoop supports women at all stages of life.
Key take home messages:
Optimal glycaemic management at conception (HbA1c target at 6.5%) and tight glycaemic targets (70% in TIRp 3.5 – 7.8 mmol/L (63 – 140mg/dL) throughout pregnancy are essential to minimise the risk of obstetric and neonatal complications
myLoop powered by CamAPS FX enables women to achieve their glycaemic targets and significantly improves TIRp from early pregnancy*
Rapid optimisations with CamAPS FX leading to less worry, less work and more enjoyable pregnancies*
Less gestational hypertension and lower rates of LGA and NICU*
The AiDAPT study also confirmed that pregnant women with a hybrid closed-loop system based on the CamAPS FX algorithm have increased TIRp, less weight gain and less hypertension*
Prof Helen Murphy suggests that myLoop powered by CamAPS FX should be offered to all pregnant women with T1D and all women with T1D planning a pregnancy.*
myLoop combines the YpsoPump insulin pump with the CamAPS FX App and a sensor for continuous glucose measurement (Dexcom G6 or FreeStyle Libre 3 and FreeStyle Libre 3 Plus).
* Lee TTM, et al. AiDAPT: automated insulin delivery amongst pregnant women with type 1 diabetes: a multicentre randomized controlled trial - study protocol. BMC Pregnancy Childbirth. 2022 Apr 5;22(1):282.
Disclaimer
The product images are for illustrative purposes only.
mylife and YpsoPump are registered trademarks of Ypsomed AG in several countries.
CamAPS is a registered trademark of CamDiab Ltd.
Dexcom and Dexcom G6 are registered trademarks of Dexcom, Inc. in the United States and/or other countries.
The sensor housing, FreeStyle, Libre, and related brand marks are marks of Abbott and used with permission.
The Bluetooth® word mark and logos are registered trademarks owned by Bluetooth SIG, Inc., and any use of such marks by Ypsomed is under license.Other trademarks are the property of their respective owners.
mylife Loop with Freestyle Libre3/Libre 3 Plus: The innovations described are available in selected countries and expanding to further countries soon. Expansion is contingent upon local regulatory approval.Insulin pumps and Automated Insulin Delivery (AID) systems can improve glucose management but do not remove the risk of diabetic ketoacidosis (DKA). Because these systems use only rapid-acting insulin, any interruption in insulin delivery (e.g., infusion-set failure, occlusion, empty reservoir, or device malfunction) can rapidly lead to ketosis and DKA, even if glucose levels are not markedly elevated.
Healthcare professionals should ensure that users understand the risk of DKA associated with pump and AID therapy, particularly in situations where insulin delivery may be interrupted. Users should be trained to recognise and troubleshoot delivery issues promptly, know when and how to check for ketones and seek urgent medical assistance. Advise to always keep a reliable backup method of insulin delivery available.This information is provided for general educational purposes and is intended for healthcare professionals. It does not replace individual clinical judgement or patient-specific medical advice.